Glucose sensing and signaling in Saccharomyces cerevisiae through the Rgt2 glucose sensor and casein kinase I
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چکیده
منابع مشابه
Glucose signaling in Saccharomyces cerevisiae.
Eukaryotic cells possess an exquisitely interwoven and fine-tuned series of signal transduction mechanisms with which to sense and respond to the ubiquitous fermentable carbon source glucose. The budding yeast Saccharomyces cerevisiae has proven to be a fertile model system with which to identify glucose signaling factors, determine the relevant functional and physical interrelationships, and c...
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How eukaryotic cells sense availability of glucose, their preferred carbon and energy source, is an important, unsolved problem. Bakers' yeast (Saccharomyces cerevisiae) uses two glucose transporter homologs, Snf3 and Rgt2, as glucose sensors that generate a signal for induction of expression of genes encoding hexose transporters (HXT genes). We present evidence that these proteins generate an ...
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Cells of the yeast Saccharomyces cerevisiae have an exquisite preference for high concentrations of glucose compared to other sugars or carbon sources. The likely explanation is that glucose is the best fermentable sugar, i.e., the sugar that allows the yeast to accumulate most rapidly high levels of ethanol, which are strongly inhibitory to competing microorganisms. To accomplish rapid ferment...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2004
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.0305901101